Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537598 | 0.89 | KCNH2 (0.44) | L3MBTL1POLBTSHRALDH1A1KDM4E | |
| SCHEMBL8482730 | 0.88 | TSHR (0.49) | L3MBTL1POLBRAB9ATSHRALDH1A1 | |
| SCHEMBL9315964 | 0.80 | ITGB3 (0.47) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8537608 | 0.80 | L3MBTL1 (0.54) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8478663 | 0.80 | EGFR (0.49) | L3MBTL1POLBRAB9AALDH1A1KDM4E | |
| SCHEMBL8482606 | 0.80 | L3MBTL1 (0.43) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8478273 | 0.79 | TSHR (0.58) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8478625 | 0.79 | EGFR (0.45) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8478670 | 0.75 | TSHR (0.70) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8482310 | 0.75 | ALDH1A1 (0.45) | L3MBTL1POLBHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485045-B1 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0485045-A2 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-13 | — | — | EP | disclosed |