Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315956 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BL3MBTL1POLBALDH1A1 | |
| SCHEMBL8482756 | 0.90 | TSHR (0.41) | ITGB3ITGA2BL3MBTL1POLBTSHR | |
| SCHEMBL8482631 | 0.83 | ALDH1A1 (0.37) | ITGB3ITGA2BL3MBTL1POLBTSHR | |
| SCHEMBL8482341 | 0.80 | ALDH1A1 (0.37) | L3MBTL1POLBALDH1A1KDM4EKMT2A | |
| SCHEMBL8537606 | 0.80 | L3MBTL1 (0.56) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL5557226 | 0.75 | KDM4E (0.41) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8478663 | 0.73 | EGFR (0.49) | ITGB3ITGA2BL3MBTL1POLBRAB9A | |
| SCHEMBL8478625 | 0.72 | EGFR (0.45) | ITGB3ITGA2BL3MBTL1POLBRAB9A | |
| SCHEMBL8537608 | 0.72 | L3MBTL1 (0.54) | L3MBTL1POLBRAB9ATSHRHSD17B10 | |
| SCHEMBL8038136 | 0.72 | SIGMAR1 (0.62) | TSHRALDH1A1KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |