Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.54 |
| ▸ | MMP1 | P03956 | 12/20 | 0.54 |
| ▸ | MMP9 | P14780 | 9/20 | 0.54 |
| ▸ | MMP2 | P08253 | 11/20 | 0.52 |
| ▸ | MMP8 | P22894 | 4/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.52 |
| ▸ | MMP13 | P45452 | 3/20 | 0.52 |
| ▸ | MMP14 | P50281 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | MMP20 | O60882 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP10 | P09238 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP15 | P51511 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.40 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098019 | 0.88 | MMP1 (0.67) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL9714246 | 0.88 | MMP1 (0.67) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL8777512 | 0.83 | MMP3 (0.59) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL8050661 | 0.77 | MMP1 (0.48) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL4634097 | 0.77 | MMP1 (0.71) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL4634101 | 0.77 | MMP1 (0.71) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL8773906 | 0.77 | MME (0.55) | MMP9MMP2MMP8MMP13MMP7 | |
| SCHEMBL15116513 | 0.75 | KISS1R (0.43) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL20054394 | 0.75 | KISS1R (0.43) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL9068163 | 0.73 | CTSS (0.44) | MMP3MMP1MMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849951-A | Synthesis of carboxylic and hydroxamic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
| EP-0812312-A1 | SYNTHESIS OF CARBOXYLIC AND HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026918-A1 | SYNTHESIS OF CARBOXYLIC AND HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-09-06 | — | — | WO | disclosed |