Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | RRM2 | P31350 | 1/20 | 0.41 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066930 | 0.89 | BIRC2 (0.46) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL8773913 | 0.83 | LTA4H (0.49) | CTSSCTSKMMP2KMT2A | |
| SCHEMBL8773895 | 0.82 | MME (0.54) | MMEMMP2MMP9MMP7MMP12 | |
| SCHEMBL8773904 | 0.81 | MME (0.53) | MMEMMP2MMP9MMP7MMP12 | |
| SCHEMBL1915928 | 0.81 | SLC1A3 (0.44) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL1705392 | 0.81 | SLC1A3 (0.44) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL4633094 | 0.81 | SLC1A3 (0.44) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL9068163 | 0.81 | CTSS (0.44) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL8050661 | 0.80 | MMP1 (0.48) | MMECTSLCTSBCTSSCTSK | |
| SCHEMBL7368385 | 0.80 | MME (0.81) | MMEALDH1A1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793643-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016027-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-05-30 | — | — | WO | disclosed |