Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542018 | 0.76 | CYP1A2 (0.45) | PLAUMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8431259 | 0.72 | RXFP1 (0.43) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL8539549 | 0.70 | KDM4E (0.47) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL4714552 | 0.69 | PLAU (0.60) | PLAUF2F13A1TGM2MAPT | |
| SCHEMBL8542779 | 0.69 | MAPT (0.43) | MAPTKMT2ANPC1RAB9AMEN1 | |
| Bicarbonate SCHEMBL8492631 | 0.69 | NPC1 (0.61) | PLAUKMT2ANPC1RAB9ANLRP3 | |
| Bicarbonate SCHEMBL27820322 | 0.69 | NPC1 (0.61) | PLAUKMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL8430795 | 0.68 | CA12 (0.40) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL7131886 | 0.68 | UNG (0.42) | MMP1MMP2MMP9KMT2AALDH1A1 | |
| SCHEMBL8544650 | 0.67 | PARP1 (0.42) | PLAUKMT2ARAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |