Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535356 | 0.84 | TBXAS1 (0.48) | HTTTBXAS1NAMPTALDH1A1GAA | |
| SCHEMBL8535819 | 0.84 | TBXAS1 (0.48) | HTTTBXAS1NAMPTALDH1A1GAA | |
| SCHEMBL8538925 | 0.78 | TBXAS1 (0.46) | TBXAS1MEN1KMT2A | |
| SCHEMBL10569165 | 0.76 | MMP13 (0.66) | MMP13MMP8HTTNPSR1MMP1 | |
| SCHEMBL8538995 | 0.76 | TBXAS1 (0.57) | HTTTBXAS1MMP1NAMPTALDH1A1 | |
| SCHEMBL8537670 | 0.76 | TBXAS1 (0.57) | HTTTBXAS1MMP1NAMPTALDH1A1 | |
| SCHEMBL8535738 | 0.75 | HRH3 (0.47) | HTTTBXAS1NPSR1NAMPTMEN1 | |
| SCHEMBL6820212 | 0.75 | MMP8 (0.60) | MMP13MMP8HTTNPSR1MMP1 | |
| SCHEMBL8537671 | 0.74 | TBXAS1 (0.45) | HTTTBXAS1NAMPTALDH1A1GAA | |
| SCHEMBL8538862 | 0.74 | TBXAS1 (0.45) | HTTTBXAS1NAMPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |