Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543960 | 0.78 | HDAC3 (0.43) | KCNK3KCNK9MEN1KMT2AALDH1A1 | |
| SCHEMBL8538376 | 0.74 | F2R (0.38) | F2RKCNK3KCNK9MEN1KMT2A | |
| SCHEMBL5354517 | 0.71 | L3MBTL1 (0.60) | KCNK3KCNK9MEN1KMT2AALDH1A1 | |
| SCHEMBL1185244 | 0.70 | KMT2A (0.58) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL8544650 | 0.69 | PARP1 (0.42) | KCNK3KCNK9MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839558 | 0.69 | KMT2A (0.57) | MEN1KMT2APARP1PARP15PARP10 | |
| Hydrochloric Acid SCHEMBL29568124 | 0.69 | KMT2A (0.57) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL895690 | 0.69 | MEN1 (0.63) | MEN1KMT2AALDH1A1PARP1PARP15 | |
| SCHEMBL6930688 | 0.68 | KMT2A (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2546537 | 0.68 | MEN1 (0.61) | MEN1KMT2AALDH1A1PARP1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |