Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 6/20 | 0.32 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542057 | 0.79 | HDAC3 (0.40) | CA1CA2CA4MAPK1 | |
| SCHEMBL8539554 | 0.75 | CA1 (0.38) | CA1CA2CA4NPC1RAB9A | |
| SCHEMBL8538542 | 0.74 | NPC1 (0.43) | CA1CA2CA4NPC1RAB9A | |
| SCHEMBL8538372 | 0.74 | F2R (0.44) | F2RNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8538198 | 0.74 | CA1 (0.38) | CA1CA2CA4NPC1RAB9A | |
| SCHEMBL8542600 | 0.73 | ERCC5 (0.41) | CA1CA2CA4NPC1RAB9A | |
| SCHEMBL8542579 | 0.73 | CA1 (0.39) | CA1CA2CA4NPC1RAB9A | |
| SCHEMBL8537256 | 0.72 | L3MBTL1 (0.40) | CA1CA2CA4NPC1SMN1; SMN2 | |
| SCHEMBL6777725 | 0.72 | RAB9A (0.50) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8542659 | 0.71 | CA1 (0.38) | CA1CA2CA4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |