Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540200 | 0.73 | ITGB3 (0.41) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL8539100 | 0.70 | ADRA2A (0.39) | ITGB3ITGAVADRA2AADRA1AHTR7 | |
| SCHEMBL11162946 | 0.70 | NISCH (0.59) | ITGB3ITGAVADRA2AADRA1AHTR7 | |
| SCHEMBL17887763 | 0.69 | HTR1D (0.59) | HTR1DADRA2AADRA1APTGIRADRA2B | |
| SCHEMBL30801516 | 0.68 | ACHE (0.66) | — | |
| SCHEMBL8538800 | 0.65 | ITGB3 (0.39) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL13017190 | 0.65 | ADRA2A (0.66) | HTR1DADRA2AADRA1APTGIRADRA2B | |
| SCHEMBL11762296 | 0.64 | ADRA2A (0.59) | HTR1DADRA2AADRA1AHTR7PTGIR | |
| SCHEMBL6788672 | 0.64 | ADRA2A (0.59) | HTR1DADRA2AADRA1AHTR7PTGIR | |
| SCHEMBL11764088 | 0.63 | PTGIR (0.69) | ADRA2AADRA1APTGIRADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |