Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 5/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538385 | 0.87 | KCNK3 (0.43) | KCNK3KCNK9NPC1RAB9AKMT2A | |
| SCHEMBL8538615 | 0.85 | RXFP1 (0.40) | KCNK3KCNK9MAPK1KDM4E | |
| SCHEMBL8539554 | 0.85 | CA1 (0.38) | KCNK3KCNK9NPC1RAB9AKMT2A | |
| SCHEMBL8542364 | 0.84 | CES2 (0.47) | KCNK3KCNK9NPC1RAB9AKMT2A | |
| SCHEMBL8538807 | 0.84 | KCNK3 (0.42) | KCNK3KCNK9NPC1RAB9AKMT2A | |
| SCHEMBL8536780 | 0.83 | MEN1 (0.39) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL8542388 | 0.82 | ATIC (0.34) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL8542422 | 0.80 | PARP1 (0.36) | KCNK3KCNK9NPC1RAB9AKMT2A | |
| SCHEMBL8538564 | 0.80 | PARP1 (0.40) | KCNK3KCNK9NPC1RAB9AKMT2A | |
| SCHEMBL8538094 | 0.78 | CES2 (0.42) | KCNK3KCNK9NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |