Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541184 | 0.91 | RAB9A (0.39) | RAB9AMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL8542569 | 0.77 | ROCK1 (0.46) | RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8539554 | 0.75 | CA1 (0.38) | RAB9AMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL8537256 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1PARP1PARP15 | |
| SCHEMBL6777725 | 0.74 | RAB9A (0.50) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8542600 | 0.73 | ERCC5 (0.41) | RAB9AMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL8538084 | 0.72 | ITGB3 (0.47) | — | |
| SCHEMBL8538572 | 0.72 | KMT2A (0.36) | RAB9AMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL8538198 | 0.71 | CA1 (0.38) | RAB9AMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL8538622 | 0.71 | ITGB3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |