Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538683 | 0.82 | KMT2A (0.39) | CYP19A1PTPN1KMT2AHPGDKDM4E | |
| SCHEMBL8539122 | 0.76 | CYP19A1 (0.36) | CYP19A1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL8538590 | 0.72 | ALDH1A1 (0.38) | KMT2AHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL11792467 | 0.70 | MEN1 (0.45) | KMT2AHPGDALDH1A1KDM4EMAPT | |
| SCHEMBL7397801 | 0.69 | SMN1; SMN2 (0.54) | CYP19A1KMT2AHPGDMAOBALDH1A1 | |
| SCHEMBL6952506 | 0.68 | XDH (0.51) | KMT2AHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL8535277 | 0.65 | BCL2 (0.38) | KMT2AHPGDALDH1A1KDM4EMAPT | |
| SCHEMBL6964231 | 0.65 | EDNRA (0.51) | CYP19A1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6960232 | 0.64 | SMN1; SMN2 (0.42) | KMT2AALDH1A1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL11056617 | 0.63 | NSD2 (0.51) | CYP19A1KMT2AHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |