Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.39 |
| ▸ | CA1 | P00915 | 9/20 | 0.39 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | CA6 | P23280 | 9/20 | 0.39 |
| ▸ | CA5A | P35218 | 9/20 | 0.39 |
| ▸ | CA7 | P43166 | 9/20 | 0.39 |
| ▸ | CA9 | Q16790 | 9/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 9/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 9/20 | 0.39 |
| ▸ | CA4 | P22748 | 8/20 | 0.39 |
| ▸ | CA3 | P07451 | 8/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538974 | 1.00 | CA12 (0.39) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8543281 | 0.99 | CA12 (0.37) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8540501 | 0.96 | CA12 (0.35) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8538912 | 0.94 | CCR2 (0.34) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8544558 | 0.85 | CA12 (0.37) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8543067 | 0.85 | CA12 (0.37) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8540494 | 0.84 | CA12 (0.35) | CA12CA1CA2CA6CA5A | |
| SCHEMBL8539018 | 0.84 | TAS1R3 (0.31) | CNR2 | |
| SCHEMBL8539035 | 0.83 | SLC9A1 (0.41) | — | |
| SCHEMBL6935261 | 0.83 | SLC9A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |