Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541311 | 0.87 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2CNR2 | |
| SCHEMBL8540501 | 0.87 | CA12 (0.35) | CNR2 | |
| SCHEMBL8543281 | 0.85 | CA12 (0.37) | — | |
| SCHEMBL8538912 | 0.84 | CCR2 (0.34) | CNR2 | |
| SCHEMBL6935156 | 0.84 | SLC9A1 (0.40) | — | |
| SCHEMBL8538974 | 0.84 | CA12 (0.39) | CNR2 | |
| SCHEMBL8538609 | 0.84 | CA12 (0.39) | CNR2 | |
| SCHEMBL8542680 | 0.82 | TAS1R3 (0.31) | TAS1R3TAS1R1 | |
| SCHEMBL8540504 | 0.79 | ACHE (0.33) | — | |
| SCHEMBL8541620 | 0.78 | DDR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |