Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542776 | 0.85 | ACHE (0.58) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL9316755 | 0.83 | OPRM1 (0.52) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL8544539 | 0.83 | PARP14 (0.53) | — | |
| SCHEMBL8539614 | 0.82 | ACHE (0.52) | ACHEOPRM1OPRK1 | |
| SCHEMBL8542915 | 0.82 | OPRK1 (0.50) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL8539650 | 0.81 | ACHE (0.46) | ACHE | |
| SCHEMBL8541500 | 0.80 | ACHE (0.43) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL8538305 | 0.79 | OPRK1 (0.48) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL8543721 | 0.79 | ACHE (0.45) | ACHE | |
| SCHEMBL8546135 | 0.79 | ACHE (0.47) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5591856-A | CHEMICAL INTERMEDIATES, TREATMENT OF ALZHEIMER'S DISEASE | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1997-01-07 | — | — | US | disclosed |
| US-5554750-A | TO RELIEVE MEMORY DYSFUNCTIONS; TREATMENT OF ALZHEMER*S | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5405845-A | Administering to relieve memory dysfunction; treatment of Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5338739-A | Memory dysfunction relieving compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-08-16 | — | — | US | disclosed |