Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.52 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542776 | 0.89 | ACHE (0.58) | OPRM1OPRK1OPRD1ACHETHRB | |
| SCHEMBL8542915 | 0.85 | OPRK1 (0.50) | OPRM1OPRK1OPRD1ACHE | |
| SCHEMBL8539296 | 0.83 | ACHE (0.50) | OPRM1OPRK1OPRD1ACHE | |
| SCHEMBL8539614 | 0.83 | ACHE (0.52) | OPRM1OPRK1ACHE | |
| SCHEMBL8538305 | 0.82 | OPRK1 (0.48) | OPRM1OPRK1OPRD1ACHETHRB | |
| SCHEMBL8539650 | 0.82 | ACHE (0.46) | ACHE | |
| SCHEMBL8872363 | 0.81 | THRB (0.60) | OPRM1OPRK1THRBKDM2B | |
| SCHEMBL8541500 | 0.81 | ACHE (0.43) | OPRM1OPRK1OPRD1ACHE | |
| SCHEMBL8543721 | 0.80 | ACHE (0.45) | ACHE | |
| SCHEMBL8546135 | 0.80 | ACHE (0.47) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338739-A | Memory dysfunction relieving compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-08-16 | — | — | US | disclosed |