Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SPR | P35270 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539181 | 0.90 | HTR6 (0.56) | HTR6MEN1KMT2ASPRKDM4E | |
| SCHEMBL8544819 | 0.89 | HTR6 (0.59) | HTR6MEN1KMT2A | |
| SCHEMBL351519 | 0.82 | MTNR1A (0.64) | MEN1KMT2A | |
| SCHEMBL8539408 | 0.78 | MAPT (0.49) | MEN1KMT2AKDM4E | |
| SCHEMBL3367245 | 0.77 | IDO1 (0.59) | MEN1KMT2AKDM4E | |
| SCHEMBL7238856 | 0.76 | GFER (0.66) | MEN1KMT2A | |
| Benzene SCHEMBL27406056 | 0.75 | MTNR1A (0.68) | MEN1KMT2ASPRKDM4E | |
| SCHEMBL3961886 | 0.75 | HTR6 (0.76) | HTR6 | |
| SCHEMBL3297282 | 0.74 | HTR6 (0.76) | HTR6 | |
| SCHEMBL3957568 | 0.74 | HTR6 (0.75) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |