Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539413 | 0.89 | HTR6 (0.56) | HTR6MEN1KMT2A | |
| SCHEMBL4169893 | 0.83 | BRD4 (0.53) | HTR6PTGDR2BRD4GAAMAPT | |
| SCHEMBL9370964 | 0.82 | SPR (0.64) | HTR6HPGDCYP2C19MAPT | |
| SCHEMBL4350200 | 0.81 | HPGD (0.57) | HTR6HPGDCYP2C19 | |
| SCHEMBL892530 | 0.80 | HPGD (0.69) | HPGDCYP2C19 | |
| SCHEMBL8539181 | 0.78 | HTR6 (0.56) | HTR6MEN1KMT2AMAPT | |
| SCHEMBL8544817 | 0.78 | GAA (0.53) | PTGDR2MEN1KMT2ABRD4GAA | |
| SCHEMBL4160229 | 0.78 | BRD4 (0.46) | HTR6BRD4GAAMAPT | |
| SCHEMBL3961886 | 0.75 | HTR6 (0.76) | HTR6 | |
| SCHEMBL3297282 | 0.75 | HTR6 (0.76) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |