SCHEMBL8540215

SCHEMBL8540215

COC(=O)C(F)(F)OC(C)OC(C)OC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2152702 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL7558553 0.71 CA1 (0.40) ALDH1A1
SCHEMBL19300076 0.69 DGAT1 (0.39) ALDH1A1DGAT1
SCHEMBL7559623 0.69 CES2 (0.42)
SCHEMBL11216608 0.66 CTRB1 (0.39) ALDH1A1DGAT1
SCHEMBL21375478 0.66 CTRB1 (0.39) ALDH1A1DGAT1
SCHEMBL11938228 0.66 DGAT1 (0.36) ALDH1A1DGAT1
SCHEMBL765780 0.66 DGAT1 (0.41) ALDH1A1DGAT1
SCHEMBL18136749 0.66 DGAT1 (0.36) ALDH1A1DGAT1
SCHEMBL28073103 0.65 DGAT1 (0.33) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0736078-B1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION MINNESOTA MINING & MFG (US) 1998-06-24 EP disclosed
EP-0736078-A1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-09 EP disclosed
US-5474705-A Electrooptical displays MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-12-12 US disclosed
WO-1995017481-A1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-29 WO disclosed