SCHEMBL8540389

SCHEMBL8540389

CN(C)C=NS(=O)(=O)c1c2c(O)cccc2nn1C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.38
▸ GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9243159 0.81 — —
SCHEMBL8539127 0.78 CDK2 (0.35) —
SCHEMBL8537561 0.77 LMNA (0.33) LMNAGAA
SCHEMBL9243156 0.74 — —
SCHEMBL1131049 0.63 GAA (0.43) LMNAGAA
SCHEMBL1131052 0.63 GAA (0.43) LMNAGAA
SCHEMBL8538654 0.62 PRMT5 (0.37) LMNA
SCHEMBL8536634 0.62 PARP1 (0.36) GAA
SCHEMBL13719062 0.62 LMNA (0.45) LMNAGAA
SCHEMBL4972178 0.61 LMNA (0.70) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657450-B1 INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF KUMIAI CHEMICAL INDUSTRY CO (JP) 1998-09-09 — — EP disclosed
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