⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540389 | 0.81 | LMNA (0.38) | — | |
| SCHEMBL9243156 | 0.79 | — | — | |
| SCHEMBL8539127 | 0.77 | CDK2 (0.35) | — | |
| SCHEMBL23475665 | 0.62 | BCAT1 (0.46) | — | |
| SCHEMBL8536634 | 0.61 | PARP1 (0.36) | — | |
| SCHEMBL8538654 | 0.61 | PRMT5 (0.37) | — | |
| SCHEMBL11164601 | 0.57 | ALDH1A1 (0.44) | — | |
| SCHEMBL8535592 | 0.57 | PTGS1 (0.40) | — | |
| SCHEMBL25236329 | 0.54 | ALDH1A1 (0.38) | — | |
| SCHEMBL17866965 | 0.52 | ACHE (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657450-A1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KumaiI Chemical Industry Co., Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |