SCHEMBL8537561

SCHEMBL8537561

CN(C)C=NS(=O)(=O)c1c2c(OCCF)cccc2nn1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.33
▸ GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9241626 0.84 — —
SCHEMBL8537910 0.81 NCF1 (0.34) LMNA
SCHEMBL9241622 0.78 ACKR3 (0.32) —
SCHEMBL8540389 0.77 LMNA (0.38) LMNAGAA
SCHEMBL27340761 0.69 NCF1 (0.34) LMNA
SCHEMBL8539150 0.66 ADRA2A (0.39) LMNA
SCHEMBL16093682 0.61 L3MBTL1 (0.39) LMNAGAA
SCHEMBL9243159 0.60 — —
SCHEMBL25362328 0.59 LMNA (0.39) LMNAGAA
SCHEMBL22600970 0.59 LMNA (0.39) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657450-B1 INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF KUMIAI CHEMICAL INDUSTRY CO (JP) 1998-09-09 — — EP disclosed
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