Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637455 | 0.94 | LTA4H (0.51) | LTA4HTBXAS1KCNA3PLA2G2ATAAR1 | |
| SCHEMBL8639331 | 0.90 | LTA4H (0.49) | LTA4HKCNA3PLA2G2ATAAR1HRH3 | |
| SCHEMBL11581355 | 0.83 | TAAR1 (0.53) | LTA4HTBXAS1KCNA3TAAR1HRH3 | |
| SCHEMBL8538142 | 0.82 | NPC1 (0.48) | TBXAS1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8641804 | 0.80 | TAAR1 (0.59) | LTA4HTAAR1HRH3CYP1A2CYP2D6 | |
| SCHEMBL8540514 | 0.79 | TBXAS1 (0.44) | TBXAS1TAAR1HRH3CYP1A2CYP3A4 | |
| SCHEMBL8635977 | 0.78 | LTA4H (0.44) | LTA4HCYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL8538925 | 0.77 | TBXAS1 (0.46) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL2942858 | 0.77 | TAAR1 (0.62) | TBXAS1TAAR1HRH3CYP2D6 | |
| SCHEMBL8307657 | 0.76 | LTA4H (0.56) | LTA4HTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |