Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541280 | 0.88 | ADRA1D (0.37) | — | |
| SCHEMBL8539005 | 0.83 | LMNA (0.41) | AR | |
| SCHEMBL8539073 | 0.82 | ADRA1D (0.35) | ALDH1A1AR | |
| SCHEMBL8539065 | 0.82 | ADRA1D (0.35) | MAOB | |
| SCHEMBL8540604 | 0.82 | ADRA1D (0.35) | AR | |
| SCHEMBL7902963 | 0.80 | ADRA1D (0.45) | — | |
| SCHEMBL8543244 | 0.80 | ADRA1D (0.45) | — | |
| SCHEMBL8539076 | 0.78 | MAPT (0.36) | ALDH1A1AR | |
| SCHEMBL8540662 | 0.77 | ADRB1 (0.35) | ALDH1A1RXFP1 | |
| SCHEMBL14966095 | 0.76 | ADRA1D (0.35) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600675-B1 | Indoline compounds for the treatment of dysuria | KISSEI PHARMACEUTICAL (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5387603-A | Treating dysuria (painful urination) with less hypotension; FDA Orange book listed patent for silodosin | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0600675-A1 | Indoline compounds for the treatment of dysuria | Kissei Pharmaceutical Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |