Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098261 | 0.76 | SMN1; SMN2 (0.49) | POLBHRH3ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL8542137 | 0.76 | BCHE (0.45) | OPRM1ACHEOPRK1 | |
| SCHEMBL8543401 | 0.73 | USP2 (0.47) | POLBHRH3ALDH1A1KDM4EHTT | |
| SCHEMBL8541194 | 0.70 | DRD2 (0.59) | OPRM1TSHRALDH1A1GAAKDM4E | |
| SCHEMBL537320 | 0.70 | SIGMAR1 (0.49) | SIGMAR1TSHRPOLBPDK1PDK2 | |
| SCHEMBL8539303 | 0.70 | DRD3 (0.47) | SIGMAR1 | |
| SCHEMBL22201130 | 0.69 | CHRNB2 (0.53) | OPRM1TSHRALDH1A1GAAKDM4E | |
| SCHEMBL2172790 | 0.69 | CHRNB2 (0.53) | OPRM1TSHRALDH1A1GAAKDM4E | |
| SCHEMBL2262334 | 0.69 | CASR (0.44) | OPRM1SIGMAR1TSHRPOLBCASR | |
| SCHEMBL8540323 | 0.68 | ALDH1A1 (0.45) | OPRM1TSHRALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |