Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540362 | 0.75 | LIPE (0.52) | ALDH1A1KMT2AKDM4EOPRK1OPRM1 | |
| SCHEMBL8540467 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EGAATSHRHTT | |
| Carbamic Acid SCHEMBL8540366 | 0.71 | RECQL (0.46) | ALDH1A1KMT2AKDM4EGAATSHR | |
| SCHEMBL8537772 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EGAATSHR | |
| SCHEMBL9250795 | 0.68 | OPRK1 (0.47) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL8544449 | 0.68 | OPRM1 (0.41) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL7482587 | 0.68 | GRIN2D (0.37) | KMT2AKDM4EGAASMN1; SMN2PRMT5 | |
| SCHEMBL8538897 | 0.67 | ALDH1A1 (0.66) | ALDH1A1KMT2AKDM4EGAATSHR | |
| SCHEMBL8538305 | 0.67 | OPRK1 (0.48) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL8541194 | 0.66 | DRD2 (0.59) | ALDH1A1KDM4EGAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |