Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.62 |
| ▸ | MAOB | P27338 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PPIA | P62937 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29470781 | 1.00 | MAOA (0.62) | MAOAMAOBMEN1KMT2APPIA | |
| SCHEMBL855289 | 0.84 | MAPT (0.61) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL30539323 | 0.81 | F7 (0.50) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL22049536 | 0.78 | MAOB (0.57) | MAOAMAOBMEN1KMT2AGAA | |
| SCHEMBL8184153 | 0.78 | MEN1 (0.73) | MAOBMEN1KMT2APPIALMNA | |
| SCHEMBL11575984 | 0.78 | MAPK14 (0.60) | MAOAMAOBGAAMAPTMAPK14 | |
| SCHEMBL8184157 | 0.77 | MAOA (0.51) | MAOAMAOBMEN1KMT2APPIA | |
| SCHEMBL24102359 | 0.76 | MAOA (0.55) | MAOAMAOBLMNAGAAMAPT | |
| SCHEMBL6216899 | 0.76 | MAOA (0.59) | MAOAMAOBLMNAGAAMAPT | |
| SCHEMBL854664 | 0.76 | MAOA (0.62) | MAOAMAOBLMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4570901-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | Buddhist Tzu Chi Medical Foundation (TW) | 2025-06-18 | — | — | EP | claimed |
| US-20250188411-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) | 2025-06-12 | — | — | US | claimed |
| US-12459950-B2 | Selective inhibitors of protein arginine methyltransferase 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2025-11-04 | — | — | US | disclosed |
| US-12440506-B2 | Selective inhibitors of protein arginine methyltransferase 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2025-10-14 | — | — | US | disclosed |
| EP-4570901-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | Buddhist Tzu Chi Medical Foundation (TW) | 2025-06-18 | — | — | EP | disclosed |
| CN-120137900-A | Method for selectively removing undifferentiated pluripotent stem cells | 佛教慈济医疗财团法人 | 2025-06-13 | — | — | CN | disclosed |
| US-20250188411-A1 | METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS | BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) | 2025-06-12 | — | — | US | disclosed |
| EP-4567028-A1 | PHTHALAZINONE DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2025-06-11 | — | — | EP | disclosed |
| EP-4330235-B1 | PHTHALAZINONE DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-02-12 | — | — | EP | disclosed |
| US-20240239757-A1 | PHTHALAZINONE DERIVATES AS NLRP3 INFLAMMASOME INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-18 | — | — | US | disclosed |
| US-20240239757-A1 | PHTHALAZINONE DERIVATES AS NLRP3 INFLAMMASOME INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-18 | — | — | US | disclosed |
| US-5104882-A | Leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1992-04-14 | — | — | US | disclosed |
| EP-0399818-A1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC. (CA) | 1990-11-28 | — | — | EP | disclosed |
| US-4803192-A | COLORLESS DYE, AN AMINOPHENYLINDOLYLPHTHALIDE AND AN ELECTRON ACCEPTOR | FUJI PHOTO FILM CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0048539-B1 | ISOQUINOLYLOXY(AMINO)PHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1985-08-28 | — | — | EP | disclosed |
| US-4409017-A | Herbicidal isoquinolinoxy- or isoquinolinamino-phenoxy alkane carboxylic acid derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-10-11 | — | — | US | disclosed |
| EP-0048539-A1 | Isoquinolyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-03-31 | — | — | EP | disclosed |
| US-4086350-A | FLUORO, CHLORO AND CYANO SUBSTITUTED 4-(9-XANTHENYLIDENE, 9-THIOXANTHENYLIDENE OR 11(6H)-DIBENZO(B,E)OXEPINYLIDENE)-1-METHYL-PIPERIDINES | SMITHKLINE CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-3985811-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1976-10-12 | — | — | US | disclosed |
| US-3946036-A | 6,11-Dihydro-11-oxo-dibenzo[b,e]thiepine-2-acetic acids | SANDOZ LTD. (CH) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459950-B2 | Selective inhibitors of protein arginine methyltransferase 5 (PRMT5) | PRMT5, PRMT1, PRMT6 | MAOA 3613/4885MAOB 3181/4885MEN1 2150/4885 |
| US-20240239757-A1 | PHTHALAZINONE DERIVATES AS NLRP3 INFLAMMASOME INHIBITORS | NLRP3, NLRP1, PYCARD | MAOA 2816/4885MAOB 1952/4885MEN1 2642/4885 |
| US-12440506-B2 | Selective inhibitors of protein arginine methyltransferase 5 (PRMT5) | PRMT5, PRMT1, PRMT6 | MAOA 3469/4885MAOB 2744/4885MEN1 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.