SCHEMBL855289

SCHEMBL855289

O=C1OCc2cc(Cl)ccc21

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
LMNA P02545 2/20 0.61
GAA P10253 1/20 0.61
MAOA P21397 6/20 0.59
MAOB P27338 6/20 0.59
PRF1 P14222 4/20 0.54
RECQL P46063 1/20 0.54
ALDH1A1 P00352 1/20 0.53
KCNJ1 P48048 1/20 0.49
KCNH2 Q12809 1/20 0.49
NPC1 O15118 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
METAP1 P53582 1/20 0.46
CYP3A4 P08684 1/20 0.46
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470781 0.84 MAOA (0.62) MAPTLMNAGAAMAOAMAOB
SCHEMBL854490 0.84 MAOA (0.62) MAPTLMNAGAAMAOAMAOB
SCHEMBL28425280 0.81 SRD5A1 (0.45) MAPTLMNAGAAMAOAMAOB
SCHEMBL4170867 0.80 MAPT (0.61) MAPTLMNAGAAMAOAMAOB
SCHEMBL30372059 0.80 MAPT (0.61) MAPTLMNAGAAMAOAMAOB
SCHEMBL13870462 0.78 MAPK14 (0.60) MAPTGAAMAOAMAOBALDH1A1
SCHEMBL13151923 0.76 HTR2B (0.39) MAPTLMNAGAAMAOAMAOB
SCHEMBL365201 0.76 MAPT (0.61) MAPTLMNAGAAMAOAMAOB
SCHEMBL87174 0.76 MAPT (0.61) MAPTLMNAGAAMAOAMAOB
SCHEMBL256733 0.76 MAPT (0.61) MAPTLMNAGAAMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4570901-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS Buddhist Tzu Chi Medical Foundation (TW) 2025-06-18 EP claimed
US-20250188411-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-06-12 US claimed
CN-116239635-A 2-amino-8-hydroxyquinoline nickel complex for resisting drug-resistant ovarian cancer and preparation method thereof 玉林师范学院 2023-06-09 CN claimed
US-7271273-B2 Method for the preparation of citalopram H. LUNDBECK A/S (DK) 2007-09-18 US claimed
US-20060079700-A1 Method for the preparation of citalopram H. LUNDBECK A/S (DE) 2006-04-13 US claimed
EP-1246813-B1 METHOD FOR THE PREPARATION OF CITALOPRAM LUNDBECK & CO AS H (DK) 2003-11-05 EP claimed
JP-2003519218-A 2003-06-17 JP claimed
US-20020198391-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2002-12-26 US claimed
EP-1246813-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. Lundbeck A/S (DK) 2002-10-09 EP claimed
WO-2001049672-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2001-07-12 WO claimed
US-20250289830-A1 KRAS INHIBITORS ELI LILLY AND COMPANY 2025-09-18 US disclosed
US-12351591-B2 KRas inhibitors ELI LILLY AND COMPANY (US) 2025-07-08 US disclosed
EP-4570901-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS Buddhist Tzu Chi Medical Foundation (TW) 2025-06-18 EP disclosed
CN-120137900-A Method for selectively removing undifferentiated pluripotent stem cells 佛教慈济医疗财团法人 2025-06-13 CN disclosed
US-20250188411-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-06-12 US disclosed
EP-0911320-B1 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same SHISEIDO CO LTD (JP) 2002-07-24 EP disclosed
WO-2002050067-A2 PHARMACEUTICAL HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 2002-06-27 WO disclosed
WO-2001049672-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2001-07-12 WO disclosed
US-6114325-A 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same SHISEIDO CO., LTD. (JP) 2000-09-05 US disclosed
EP-0911320-A2 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same SHISEIDO COMPANY LIMITED (JP) 1999-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060079700-A1 Method for the preparation of citalopram HTR5A, HTR3C, HTR3B MAPT 255/4885LMNA 698/4885GAA 1672/4885
US-20020198391-A1 METHOD FOR THE PREPARATION OF CITALOPRAM HTR5A, HTR3C, HTR3B MAPT 255/4885LMNA 698/4885GAA 1672/4885
US-12351591-B2 KRas inhibitors KRAS, NRAS, HRAS MAPT 4564/4885LMNA 3550/4885GAA 1287/4885
US-20250289830-A1 KRAS INHIBITORS KRAS, NRAS, HRAS MAPT 4564/4885LMNA 3550/4885GAA 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.