Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546442 | 0.87 | ALOX5 (0.51) | ALOX5ALOX12PTGS1PTGS2ALDH1A1 | |
| SCHEMBL8550646 | 0.85 | ALOX5 (0.52) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL8546788 | 0.81 | ALOX5 (0.45) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL8545824 | 0.77 | LPAR1 (0.49) | CARM1PRMT6ALOX5PTGS1PTGS2 | |
| SCHEMBL9378801 | 0.74 | ALOX5 (0.43) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL8550197 | 0.73 | MMP2 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8546575 | 0.72 | F10 (0.45) | ALOX5ALOX12PTGS1PTGS2ALDH1A1 | |
| SCHEMBL8545311 | 0.72 | ITGB3 (0.49) | ST14ALOX5PTGS1PTGS2 | |
| SCHEMBL8549962 | 0.72 | ITGB3 (0.49) | ST14ALOX5PTGS1PTGS2 | |
| SCHEMBL8546769 | 0.72 | ITGB3 (0.49) | ST14ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |