Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545311 | 0.98 | ITGB3 (0.49) | MMP2ALOX5PTGS1PTGS2ITGB3 | |
| SCHEMBL8546769 | 0.98 | ITGB3 (0.49) | MMP2ALOX5PTGS1PTGS2ITGB3 | |
| SCHEMBL8549962 | 0.98 | ITGB3 (0.49) | MMP2ALOX5PTGS1PTGS2ITGB3 | |
| SCHEMBL8546442 | 0.84 | ALOX5 (0.51) | ALOX5PTGS1PTGS2KMT2A | |
| SCHEMBL8547601 | 0.83 | ALOX5 (0.46) | MMP2ALOX5PTGS1PTGS2 | |
| SCHEMBL8547612 | 0.83 | ALOX5 (0.46) | MMP2ALOX5PTGS1PTGS2 | |
| SCHEMBL8552020 | 0.83 | ALOX5 (0.46) | MMP2ALOX5PTGS1PTGS2 | |
| SCHEMBL9474556 | 0.81 | ALOX5 (0.74) | ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8545668 | 0.80 | PARP10 (0.59) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8550223 | 0.77 | ALOX5 (0.56) | ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |