Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | FURIN | P09958 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546442 | 0.90 | ALOX5 (0.51) | ALOX5ALOX12PTGS1PTGS2PARP15 | |
| SCHEMBL8546788 | 0.86 | ALOX5 (0.45) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL8545137 | 0.85 | CARM1 (0.49) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL8547121 | 0.85 | ALOX5 (0.50) | ALOX5ALOX12PTGS1PTGS2TNKS | |
| SCHEMBL8545824 | 0.83 | LPAR1 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8141390 | 0.81 | F10 (0.44) | ALOX5ALOX12PTGS1PTGS2F2 | |
| SCHEMBL8548288 | 0.79 | ALOX5 (0.59) | ALOX5PTGS1PTGS2PARP15PARP14 | |
| SCHEMBL8546575 | 0.77 | F10 (0.45) | ALOX5ALOX12PTGS1PTGS2F10 | |
| SCHEMBL8546496 | 0.76 | NR3C1 (0.47) | ALOX5 | |
| SCHEMBL8550197 | 0.76 | MMP2 (0.49) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |