Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPR3 | P17342 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545041 | 0.88 | ELANE (0.43) | ELANEKMT2AMEN1ALDH1A1CTRB1 | |
| SCHEMBL8550797 | 0.87 | ALDH1A1 (0.42) | ELANEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6499604 | 0.86 | CTRB1 (0.56) | ELANEKMT2AMEN1ALDH1A1CTRB1 | |
| SCHEMBL7659173 | 0.84 | ATM (0.43) | ELANEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7658844 | 0.79 | CTRB1 (0.54) | ELANEKMT2AMEN1ALDH1A1CTRB1 | |
| SCHEMBL7845338 | 0.79 | ELANE (0.54) | ELANEKMT2AMEN1CTRB1 | |
| SCHEMBL8545895 | 0.78 | ALDH1A1 (0.50) | ELANEKMT2AMEN1ALDH1A1CTRB1 | |
| SCHEMBL8549764 | 0.76 | ELANE (0.47) | ELANEKMT2AMEN1ALDH1A1CTRB1 | |
| SCHEMBL6496779 | 0.75 | CTRB1 (0.56) | ELANEKMT2AMEN1ALDH1A1CTRB1 | |
| SCHEMBL6500859 | 0.74 | CTRB1 (0.53) | ELANEKMT2AMEN1ALDH1A1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |