Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890879 | 0.81 | KMT2A (0.53) | ADORA3ALDH1A1HSP90AA1HSP90AB1ADORA2A | |
| SCHEMBL8539340 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRCYP3A4GABRP | |
| SCHEMBL8074157 | 0.77 | CYP3A4 (0.48) | ALDH1A1HSD17B10TSHRCYP3A4GABRP | |
| SCHEMBL28293697 | 0.77 | ADORA3 (0.61) | ADORA3ALDH1A1HSD17B10TSHRHSP90AA1 | |
| SCHEMBL11775934 | 0.76 | CYP3A4 (0.53) | ALDH1A1HSD17B10TSHRCYP3A4HSP90AA1 | |
| SCHEMBL3088381 | 0.74 | ADORA3 (0.66) | ADORA3ALDH1A1HSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL9528103 | 0.74 | CYP3A4 (0.50) | ALDH1A1HSD17B10TSHRCYP3A4GABRP | |
| SCHEMBL28288558 | 0.73 | CYP3A4 (0.65) | ALDH1A1HSD17B10TSHRCYP3A4CYP1A2 | |
| SCHEMBL561316 | 0.73 | ADORA3 (0.64) | ADORA3ALDH1A1HSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL28343462 | 0.72 | CYP3A4 (0.69) | ALDH1A1HSD17B10TSHRCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581500-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5441949-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0581500-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |