Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | CCR3 | P51677 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553703 | 0.87 | CCR5 (0.39) | NOTUMCCR5DRD2DRD4 | |
| SCHEMBL8552339 | 0.87 | NOTUM (0.44) | NOTUMP2RX7CCR3HRH1KCNH2 | |
| SCHEMBL8551503 | 0.87 | NOTUM (0.41) | NOTUMP2RX7CCR3HRH1KCNH2 | |
| SCHEMBL8550876 | 0.86 | CCR5 (0.42) | CCR3HRH1KCNH2CCR5 | |
| SCHEMBL8552451 | 0.79 | CCR5 (0.39) | CCR3CCR5 | |
| SCHEMBL8551859 | 0.79 | ALOX5 (0.36) | DRD2DRD4 | |
| SCHEMBL8547882 | 0.73 | CCR5 (0.43) | CCR5 | |
| SCHEMBL6247724 | 0.73 | TSHR (0.37) | NOTUMCCR5 | |
| SCHEMBL6249594 | 0.72 | OPRK1 (0.55) | P2RX7CCR3HRH1KCNH2CCR5 | |
| SCHEMBL16333323 | 0.72 | OPRK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | claimed |