Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692074 | 0.85 | HPGD (0.45) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| SCHEMBL8551309 | 0.85 | RAB9A (0.48) | ALDH1A1KDM4EHTR1FNPC1RAB9A | |
| SCHEMBL8549636 | 0.83 | HTR1F (0.51) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL8547488 | 0.83 | HTR1F (0.53) | HSD17B10MAPTHTR1FCA12CA9 | |
| SCHEMBL8552580 | 0.83 | HTR1F (0.65) | ALDH1A1KDM4EMAPTHTR1FNPC1 | |
| SCHEMBL8548295 | 0.82 | RAB9A (0.51) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL8552436 | 0.81 | KMT2A (0.49) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL8552089 | 0.81 | HTR1F (0.52) | MAPTHTR1FNPC1TP53RAB9A | |
| SCHEMBL8549211 | 0.81 | HTR1F (0.49) | ALDH1A1KDM4EMAPTMAPK1HTR1F | |
| SCHEMBL8709033 | 0.79 | HTR1F (0.48) | MAPTHTR1FNPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |