Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 6/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372791 | 0.86 | KDR (0.35) | KMT2ASMOPTPN1KDRHSD17B10 | |
| SCHEMBL8554030 | 0.86 | SIGMAR1 (0.34) | SMN1; SMN2KDRHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL8551586 | 0.85 | KDR (0.34) | KMT2ASMOKDRMAPT | |
| SCHEMBL8552267 | 0.84 | HSD11B1 (0.38) | HSD11B1KMT2APTPN1SMN1; SMN2KDR | |
| SCHEMBL8374822 | 0.83 | NPSR1 (0.39) | GAASMN1; SMN2KDRHSD17B10MAPT | |
| SCHEMBL8549550 | 0.82 | KDR (0.44) | KMT2AGAASMN1; SMN2KDRHSD17B10 | |
| Hydrochloric Acid SCHEMBL8547376 | 0.81 | NPSR1 (0.39) | GAASMN1; SMN2KDRHSD17B10MAPT | |
| SCHEMBL8553998 | 0.77 | KDR (0.37) | KMT2AGAASMN1; SMN2KDRMEN1 | |
| Hydrochloric Acid SCHEMBL8548606 | 0.77 | ALDH1A1 (0.42) | KMT2AGAASMN1; SMN2KDRHSD17B10 | |
| SCHEMBL8372825 | 0.77 | ENPP3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |