Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.50 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550197 | 0.80 | MMP2 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8546769 | 0.78 | ITGB3 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8549962 | 0.78 | ITGB3 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8545311 | 0.78 | ITGB3 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8546442 | 0.77 | ALOX5 (0.51) | PARP10PARP15ALOX5PTGS1PTGS2 | |
| SCHEMBL8547601 | 0.77 | ALOX5 (0.46) | PARP10ALOX5PTGS1PTGS2 | |
| SCHEMBL8547612 | 0.77 | ALOX5 (0.46) | PARP10ALOX5PTGS1PTGS2 | |
| SCHEMBL8552020 | 0.77 | ALOX5 (0.46) | PARP10ALOX5PTGS1PTGS2 | |
| SCHEMBL8549400 | 0.77 | PARP10 (0.49) | PARP10PARP15PARP2ALOX5PTGS1 | |
| SCHEMBL8544280 | 0.75 | FURIN (0.52) | PARP10ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |