Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549491 | 1.00 | KMT2A (0.47) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8544264 | 0.89 | HSD11B1 (0.46) | KDM4EALDH1A1LMNAHTTHSD11B1 | |
| SCHEMBL8544257 | 0.89 | HSD11B1 (0.46) | KDM4EALDH1A1LMNAHTTHSD11B1 | |
| SCHEMBL8549703 | 0.85 | CNR2 (0.47) | KMT2AALDH1A1HTTSMN1; SMN2HSD11B1 | |
| SCHEMBL8549691 | 0.85 | CNR2 (0.47) | KMT2AALDH1A1HTTSMN1; SMN2HSD11B1 | |
| SCHEMBL8549494 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HSD11B1CYP17A1CYP19A1 | |
| SCHEMBL8543192 | 0.83 | HSD11B1 (0.54) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL8548918 | 0.83 | HSD11B1 (0.54) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL8549977 | 0.78 | HSD11B1 (0.44) | ALDH1A1HSD11B1EPHX1 | |
| SCHEMBL8543046 | 0.77 | KMT2A (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |