Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553647 | 0.88 | LMNA (0.43) | L3MBTL1POLBLMNATHRBEPHX1 | |
| SCHEMBL8551331 | 0.86 | POLB (0.43) | L3MBTL1POLBLMNATHRBEPHX1 | |
| SCHEMBL8590974 | 0.86 | L3MBTL1 (0.44) | L3MBTL1POLBLMNATHRBEPHX1 | |
| SCHEMBL8624368 | 0.84 | GPR119 (0.39) | GLS | |
| Hydrochloric Acid SCHEMBL8594144 | 0.81 | SMYD3 (0.38) | SMYD3MEN1KMT2AALDH1A1 | |
| SCHEMBL9409500 | 0.79 | HDAC4 (0.48) | L3MBTL1POLBLMNATHRBKMT2A | |
| SCHEMBL8550488 | 0.78 | KDM4E (0.44) | THRBEPHX1GLSKDM4EALDH1A1 | |
| SCHEMBL8625016 | 0.78 | KDM4E (0.49) | LMNAGLSMEN1KMT2AKDM4E | |
| SCHEMBL8553067 | 0.77 | GLS (0.38) | THRBGLSKDM4EALDH1A1MAPT | |
| SCHEMBL8551323 | 0.76 | GPR119 (0.43) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |