Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374822 | 0.89 | NPSR1 (0.39) | KDRENPP3ALDH1A1HPGDNPSR1 | |
| SCHEMBL8553998 | 0.88 | KDR (0.37) | KDRENPP3KMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8547376 | 0.88 | NPSR1 (0.39) | KDRENPP3ALDH1A1HPGDNPSR1 | |
| SCHEMBL8549269 | 0.82 | HSD11B1 (0.34) | KDRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8371540 | 0.81 | CCNE2 (0.32) | KDR | |
| Hydrochloric Acid SCHEMBL8553284 | 0.80 | CCNE2 (0.32) | KDR | |
| SCHEMBL8554030 | 0.80 | SIGMAR1 (0.34) | KDRENPP3ALDH1A1HPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL8548606 | 0.78 | ALDH1A1 (0.42) | KDRENPP3KMT2AALDH1A1HPGD | |
| SCHEMBL8372791 | 0.77 | KDR (0.35) | KDRKMT2AALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL8551586 | 0.76 | KDR (0.34) | KDRKMT2APOLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |