Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902880 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL7902881 | 0.81 | LTB4R (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10533234 | 0.80 | CYP2D6 (0.62) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL8544985 | 0.76 | LMNA (0.48) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8545899 | 0.76 | LMNA (0.48) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL7908882 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL27546572 | 0.73 | PYCR1 (0.60) | ALDH1A1MEN1KMT2ASLC6A4MAPT | |
| SCHEMBL9167642 | 0.72 | MEN1 (0.53) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9306766 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL12087531 | 0.71 | MEN1 (0.55) | ALDH1A1MEN1KMT2ASLC6A4PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525825-B1 | Substituted dicarboxy pyridine compounds | EG & G WALLAC OY (FI) | 1998-12-09 | — | — | EP | disclosed |
| EP-0195413-B1 | Substituted pyridine derivatives | BAXTER DIAGNOSTICS INC (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0525825-A2 | Substituted dicarboxy pyridine compounds | Dade MicroScan Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4761481-A | FLUORESCENT CHELATES, AMINE ACID COMPOUNDS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0195413-A2 | Substituted pyridine derivatives | Baxter Diagnostics Inc. (US) | 1986-09-24 | — | — | EP | disclosed |