Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309137 | 0.82 | PBRM1 (0.46) | ALDH1A1ACHENPC1 | |
| SCHEMBL10533234 | 0.79 | CYP2D6 (0.62) | ALDH1A1MAPTACHEMEN1KMT2A | |
| SCHEMBL9306776 | 0.77 | MAPT (0.47) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL12310918 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL8720282 | 0.75 | MEN1 (0.58) | ALDH1A1MAPTACHECES2CES1 | |
| SCHEMBL181572 | 0.74 | CES2 (0.78) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL10539201 | 0.73 | KMT2A (0.62) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL11593026 | 0.72 | CES2 (0.76) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL13619886 | 0.72 | ERN1 (0.56) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7911565 | 0.72 | MEN1 (0.64) | ALDH1A1MAPTCES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308754-A | Terbium compounds | KANKARE JOUKO J | 1994-05-03 | — | — | US | disclosed |