Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553845 | 0.89 | CYP1A2 (0.46) | ALDH1A1LMNANOTUMMAPTKMT2A | |
| SCHEMBL8550320 | 0.89 | NR1H2 (0.47) | AKR1C3ALDH1A1LMNANOTUMKMT2A | |
| SCHEMBL8998873 | 0.79 | AKR1C3 (0.59) | TDP1AKR1C3ALDH1A1LMNAMAPT | |
| SCHEMBL8550492 | 0.79 | CYP1A2 (0.44) | ALDH1A1MAPTKMT2AMEN1CA12 | |
| SCHEMBL8549362 | 0.79 | TDP1 (0.50) | TDP1AKR1C3ALDH1A1LMNAMAPT | |
| SCHEMBL8547980 | 0.79 | ALDH1A1 (0.50) | TDP1AKR1C3ALDH1A1LMNAMAPT | |
| SCHEMBL1994212 | 0.79 | CA12 (0.55) | TDP1ALDH1A1LMNANOTUMTAS2R14 | |
| SCHEMBL8547825 | 0.75 | SMN1; SMN2 (0.51) | TDP1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL314 | 0.75 | AKR1C3 (0.66) | TDP1AKR1C3ALDH1A1LMNAMAPT | |
| SCHEMBL24445845 | 0.73 | CA12 (0.69) | LMNANOTUMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |