Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551346 | 0.79 | NOS1 (0.41) | NOS1NOS2 | |
| SCHEMBL8552252 | 0.73 | NOS2 (0.45) | NOS2 | |
| SCHEMBL8552256 | 0.73 | NOS2 (0.45) | NOS2 | |
| SCHEMBL8550044 | 0.73 | NOS3 (0.47) | NOS1NOS2 | |
| SCHEMBL7628313 | 0.72 | NOS1 (0.40) | NOS1NOS2TP53 | |
| Hydrochloric Acid SCHEMBL6797325 | 0.70 | ALDH1A1 (0.38) | NOS1NOS2 | |
| SCHEMBL7679025 | 0.70 | NOS1 (0.43) | NOS1NOS2 | |
| SCHEMBL7511004 | 0.69 | NOS1 (0.38) | NOS1NOS2 | |
| SCHEMBL8110734 | 0.69 | ALDH1A1 (0.41) | NOS1NOS2TP53 | |
| Hydrochloric Acid SCHEMBL7684193 | 0.69 | NOS3 (0.42) | NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824523-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. Searle & Co. (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035677-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. SEARLE & CO. (US) | 1996-11-14 | — | — | WO | disclosed |