Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.56 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372536 | 0.83 | ALOX5 (0.53) | ALOX5KMT2A | |
| SCHEMBL6037547 | 0.83 | ALOX5 (0.56) | ALOX5RIPK1 | |
| SCHEMBL8546442 | 0.82 | ALOX5 (0.51) | ALOX5KMT2A | |
| SCHEMBL7217220 | 0.77 | LOXL2 (0.52) | ALOX5KMT2A | |
| SCHEMBL8550197 | 0.77 | MMP2 (0.49) | ALOX5KMT2A | |
| SCHEMBL8549962 | 0.76 | ITGB3 (0.49) | ALOX5 | |
| SCHEMBL8545311 | 0.76 | ITGB3 (0.49) | ALOX5 | |
| SCHEMBL8546769 | 0.76 | ITGB3 (0.49) | ALOX5 | |
| SCHEMBL9162595 | 0.76 | POLB (0.53) | ALOX5KMT2A | |
| SCHEMBL8547601 | 0.75 | ALOX5 (0.46) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |