Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547612 | 1.00 | ALOX5 (0.46) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8547601 | 1.00 | ALOX5 (0.46) | ALOX5PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL8550197 | 0.83 | MMP2 (0.49) | ALOX5PTGS1PTGS2MMP2 | |
| SCHEMBL8546769 | 0.82 | ITGB3 (0.49) | ALOX5PTGS1PTGS2MMP2 | |
| SCHEMBL8545311 | 0.82 | ITGB3 (0.49) | ALOX5PTGS1PTGS2MMP2 | |
| SCHEMBL8549962 | 0.82 | ITGB3 (0.49) | ALOX5PTGS1PTGS2MMP2 | |
| SCHEMBL8546442 | 0.81 | ALOX5 (0.51) | ALOX5PTGS1PTGS2ALDH1A1PARP10 | |
| SCHEMBL9474556 | 0.78 | ALOX5 (0.74) | ALOX5PTGS1PTGS2PARP10 | |
| SCHEMBL8548288 | 0.77 | ALOX5 (0.59) | ALOX5PTGS1PTGS2PARP10 | |
| SCHEMBL8545668 | 0.77 | PARP10 (0.59) | ALOX5PTGS1PTGS2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |