Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.49 |
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547901 | 0.87 | POLB (0.43) | PPARDPPARAPPARGFFAR1KDM4E | |
| SCHEMBL8546367 | 0.83 | PPARD (0.46) | PPARDPPARAPPARGAGBL2FFAR1 | |
| SCHEMBL8551360 | 0.82 | ALDH1A1 (0.46) | PPARDPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL8544759 | 0.78 | PPARD (0.41) | PPARDPPARAPPARGFFAR1KDM4E | |
| SCHEMBL8545353 | 0.77 | KDM4E (0.45) | PPARDFFAR1KDM4EALDH1A1RAB9A | |
| SCHEMBL5474625 | 0.75 | PPARD (0.62) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5023897 | 0.74 | PPARD (0.75) | PPARDPPARAPPARGFFAR1ALDH1A1 | |
| SCHEMBL8548084 | 0.74 | PPARD (0.39) | PPARDPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL8548708 | 0.73 | PTGDR2 (0.40) | PPARDPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL4481950 | 0.72 | PTGDR2 (0.42) | PPARDFFAR1KDM4EALDH1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |