Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.40 |
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545256 | 0.87 | TRPM8 (0.42) | NNMTLMNAMAPTPOLBMEN1 | |
| SCHEMBL8545155 | 0.81 | LMNA (0.41) | PTGDR2LMNAMAPTPOLBPPARG | |
| SCHEMBL8551360 | 0.76 | ALDH1A1 (0.46) | PTGDR2MAPTPOLBPPARGPPARD | |
| SCHEMBL8545353 | 0.75 | KDM4E (0.45) | PTGDR2LMNAMAPTPOLBPPARD | |
| SCHEMBL4481950 | 0.75 | PTGDR2 (0.42) | PTGDR2LMNAMAPTPOLBPPARD | |
| SCHEMBL8591973 | 0.74 | ECE1 (0.42) | PTGDR2POLBKDM4EALDH1A1 | |
| SCHEMBL11588944 | 0.74 | MAPT (0.43) | PTGDR2LMNAMAPTPOLBKDM4E | |
| SCHEMBL8550265 | 0.73 | PPARD (0.49) | PTGDR2PPARGPPARDPPARAKDM4E | |
| SCHEMBL8591219 | 0.72 | KDM5B (0.44) | PTGDR2MAPTPPARGPPARDPPARA | |
| SCHEMBL8543453 | 0.72 | CYP1A2 (0.50) | PTGDR2LMNAMAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |