Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552304 | 0.83 | CA9 (0.39) | FLT1KDRMCHR1PTGESHDAC1 | |
| SCHEMBL8211589 | 0.82 | HTR1F (0.43) | FLT1KDRMCHR1NPC1RAB9A | |
| SCHEMBL5906366 | 0.71 | HTR1F (0.45) | NPC1RAB9AHDAC1HTR1FMEN1 | |
| SCHEMBL8551441 | 0.71 | ACKR3 (0.49) | FLT1KDRMCHR1ACKR3HDAC1 | |
| Sulfuric Acid SCHEMBL8551754 | 0.71 | TMEM97 (0.43) | MCHR1ACKR3NPC1RAB9ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL8553970 | 0.67 | EGFR (0.41) | NPC1RAB9AHTR1FMAPTEGFR | |
| SCHEMBL8551502 | 0.67 | HTR1F (0.46) | NPC1RAB9AHTR1FTP53MAPT | |
| SCHEMBL8551467 | 0.65 | GRM5 (0.36) | KDRNPC1RAB9AHTR1FTP53 | |
| SCHEMBL8548549 | 0.65 | HTR1F (0.50) | FLT1KDRMCHR1ACKR3RAB9A | |
| SCHEMBL8551891 | 0.65 | HTR1F (0.49) | FLT1KDRACKR3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |