Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906366 | 0.84 | HTR1F (0.45) | HDAC1 | |
| SCHEMBL8550328 | 0.83 | FLT1 (0.37) | MCHR1FLT1KDRPTGESHDAC1 | |
| SCHEMBL8211589 | 0.83 | HTR1F (0.43) | MCHR1MAOBFLT1KDRPTGES | |
| SCHEMBL8548549 | 0.72 | HTR1F (0.50) | MCHR1FLT1KDRHDAC1 | |
| Sulfuric Acid SCHEMBL8552469 | 0.71 | TMEM97 (0.42) | MCHR1HDAC1 | |
| SCHEMBL8551588 | 0.69 | TMEM97 (0.48) | MCHR1FLT1KDRHDAC1 | |
| Oxalic Acid SCHEMBL8548077 | 0.68 | EGFR (0.41) | — | |
| SCHEMBL8548601 | 0.67 | HTR1F (0.45) | — | |
| SCHEMBL8549783 | 0.65 | GRM5 (0.37) | CA9MAOBKDR | |
| SCHEMBL8549636 | 0.64 | HTR1F (0.51) | CA9MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |